API

MELPHALAN

Drug classification

Dosage form

TABLET;ORAL

API strength per dosage

2MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

Dose

Mechanism of action

Melphalan, a bifunctional alkylating agent, forms interstrand DNA crosslinks, inhibiting DNA replication and transcription. This leads to cell cycle arrest and apoptosis in rapidly dividing tumor cells.

Indications

Side effects

Pregnancy category

Precautions

Contraindications