API

Euphorbia Prostrata Extract (100mg) + Calcium Dobesilate (500mg)

Drug classification

Vascular protective agent; specific subclass: flavonoid derivative and calcium dobesilate combination.

Dosage form

Thank OD Forte Tablet is an oral tablet formulation.

API strength per dosage

Dose

Standard adult dosing for Thank OD Forte Tablet (Euphorbia Prostrata Extract 100mg + Calcium Dobesilate 500mg) is typically one tablet once or twice daily, as directed by a physician. Safety and dosing in children, and in patients with renal or hepatic impairment, have not been well established; use with caution and consult a healthcare professional.

Mechanism of action

Thank OD Forte Tablet combines Euphorbia prostrata extract, which exhibits anti-inflammatory and hemostatic effects by inhibiting prostaglandin synthesis and reducing capillary permeability, with calcium dobesilate, which stabilizes capillary endothelium, decreases capillary permeability, and improves microcirculation, thereby reducing edema and inflammation in conditions like hemorrhoids and chronic venous insufficiency.

Indications

Treatment of Piles

Side effects

Nausea Diarrhea Fever Vertigo Headache Indigestion Abdominal pain Stomach inflammation Dizziness Contact dermatitis Allergic reaction Hypersensitivity Dryness in mouth

Pregnancy category

Safety of Euphorbia prostrata extract and calcium dobesilate in pregnancy is not established; use only if potential benefits justify potential risks to the fetus.

Precautions

Assess for hypersensitivity, monitor for gastrointestinal disturbances, caution in bleeding disorders, monitor renal and hepatic function, avoid in severe renal impairment, use with caution in pregnancy and lactation, monitor for allergic reactions, assess for drug interactions, monitor hemoglobin and blood counts periodically.

Contraindications

Hypersensitivity to Euphorbia prostrata extract, calcium dobesilate, or any excipients, active gastrointestinal bleeding, severe renal or hepatic impairment, history of agranulocytosis, pregnancy, lactation.