API

Loperamide (2mg)

Drug classification

Dosage form

Tablet

API strength per dosage

Dose

Adults: Initial dose 4 mg, then 2 mg after each loose stool; maximum 16 mg/day. Children ≥6 years: 2 mg after first loose stool, then 1 mg after each subsequent loose stool; maximum 6 mg/day (6–8 years), 8 mg/day (8–12 years). Contraindicated in children <6 years. Use caution in hepatic impairment.

Mechanism of action

Indications

Diarrhea

Side effects

Constipation Nausea Headache Stomach pain

Pregnancy category

Precautions

Contraindications

Hypersensitivity to loperamide, acute dysentery with blood in stools and high fever, acute ulcerative colitis, bacterial enterocolitis, pseudomembranous colitis, abdominal distension, children under 2 years.