API

Ceftriaxone (1000mg) + Disodium edetate (37mg) + Sulbactam (500mg)

Drug classification

Ceftriaxone: Antibiotic (cephalosporin), Sulbactam: Beta-lactamase inhibitor. Combination antibiotic.

Dosage form

API strength per dosage

Dose

Mechanism of action

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); sulbactam irreversibly inhibits bacterial β-lactamases; disodium edetate chelates divalent cations, destabilizing bacterial outer membrane and enhancing β-lactam activity. Result: bactericidal effect via inhibition of peptidoglycan cross-linking and β-lactamase-mediated resistance.

Indications

Treatment of Bacterial infections

Side effects

Injection site reactions pain swelling redness Nausea Vomiting Diarrhea

Pregnancy category

Precautions

Contraindications