API

Adapalene (0.1% w/w) + Clindamycin (1% w/w)

Drug classification

Adapalene: Retinoids; Clindamycin: Antibiotics (lincosamide); Combination: Acne therapy.

Dosage form

Topical gel

API strength per dosage

Dose

Apply a thin layer to the affected area once daily at bedtime for adults and children ≥12 years; safety and efficacy in children <12 years not established. Avoid use in pregnancy. Use with caution in lactation; avoid application to chest if breastfeeding. Adjust use in case of irritation.

Mechanism of action

Indications

Treatment of Acne

Side effects

Skin peeling Erythema skin redness Itching Dry skin Burning sensation at the site of application

Pregnancy category

Precautions

Contraindications