API

Dapagliflozin (10mg)

Drug classification

Antidiabetic (SGLT2 inhibitor)

Dosage form

Tablet

API strength per dosage

10 mg dapagliflozin per tablet

Dose

Adults: 10 mg once daily, with or without food. Not recommended for pediatric patients under 18 years. Use with caution in severe renal impairment; contraindicated in patients with eGFR <30 mL/min/1.73 m². Dose adjustment not required for mild or moderate hepatic impairment.

Mechanism of action

Indications

Treatment of Type 2 diabetes mellitus

Side effects

Polyuria Nausea Vomiting Dyslipidemia Genital fungal infection Nasopharyngitis inflammation of the throat and nasal passages Urinary tract infection

Pregnancy category

Precautions

Renal impairment, hepatic impairment, risk of ketoacidosis, hypotension, urinary tract infections, genital mycotic infections, volume depletion, elderly patients, pregnancy, breastfeeding, history of bladder cancer, concomitant diuretic use, risk of hypoglycemia with insulin or sulfonylureas, monitor renal function, discontinue before major surgery.

Contraindications