API

Etoposide

Drug classification

Antineoplastic agents (topoisomerase II inhibitor).

Dosage form

Solution For Injection

API strength per dosage

100 mg

Dose

Mechanism of action

Indications

Testicular cancer, small cell lung cancer, Hodgkin lymphoma, non-Hodgkin lymphoma, acute myeloid leukemia, gestational trophoblastic neoplasia, ovarian cancer.

Side effects

Pregnancy category

Category D

Precautions

Monitor for myelosuppression, avoid use in severe hepatic impairment, ensure adequate hydration, monitor for hypersensitivity reactions, avoid extravasation, use effective contraception, assess for infection risk, adjust dose in renal impairment, avoid live vaccines, monitor blood pressure, caution in elderly, avoid rapid infusion, monitor for secondary malignancies.

Contraindications