API

Drug classification

Dosage form

Tablet

API strength per dosage

Diloxanide Furoate BP 500 mg & Metronidazole BP…

Dose

Adults: Diloxanide furoate 500 mg and metronidazole 400 mg, three times daily for 10 days. Pediatrics: Adjust dose based on weight and age, consult specific pediatric guidelines. Special populations: Caution in liver impairment; dose adjustment may be necessary. Always verify with current clinical guidelines.

Mechanism of action

Indications

Side effects

Pregnancy category

Category B (Diloxanide Furoate), Category B (Metronidazole).

Precautions

Avoid alcohol during treatment and for at least 48 hours after, monitor for neurological symptoms, use cautiously in patients with liver disease, consider potential for drug interactions, not recommended during the first trimester of pregnancy, use caution in breastfeeding, adjust dose in renal impairment.

Contraindications

Hypersensitivity to ingredients, pregnancy (first trimester for metronidazole), liver disease, neurological disorders, blood dyscrasias, lactation, children under 2 years, alcohol consumption (during treatment and 48 hours post-metronidazole).