API

Drug classification

Analgesics (non-opioid analgesic; antipyretic)

Dosage form

Soluble Tablet

API strength per dosage

500MG

Dose

Mechanism of action

Inhibits central cyclooxygenase-2 (COX-2), reducing prostaglandin E2 synthesis in the CNS, leading to antipyresis and analgesia. Minimal peripheral COX inhibition; lacks significant anti-inflammatory effects. No direct action on opioid receptors or peripheral nociceptors. Precise molecular target: prostaglandin H2 synthase (PGHS) active site.

Indications

Side effects

Pregnancy category

Precautions

Contraindications