API

Aminosidine sulphate

Drug classification

Antibiotics (aminoglycoside antibiotic)

Dosage form

Tablet

API strength per dosage

250MG

Dose

Adults: 500 mg orally twice daily for 7–10 days. Pediatrics: 15 mg/kg/day in two divided doses for 7–10 days. Dose adjustment may be required in renal impairment; use with caution. Not recommended in pregnancy unless clearly indicated.

Mechanism of action

Indications

Amoebiasis, leishmaniasis, giardiasis, cryptosporidiosis, intestinal cestode infections, intestinal protozoal infections, adjunct in hepatic coma.

Side effects

Pregnancy category

Category D

Precautions

Contraindications

Hypersensitivity to aminoglycosides, intestinal obstruction, severe renal impairment, myasthenia gravis, Parkinson’s disease, ulcerative lesions of the bowel, pregnancy, breastfeeding.