API

Azithromycin, Fluconazole, Secnidazole

Drug classification

Azithromycin: Antibiotic (macrolide), Fluconazole: Antifungal (triazole), Secnidazole: Antiprotozoal (nitroimidazole); Antimicrobial combination.

Dosage form

Tablet

API strength per dosage

AZITHROMYCIN 1G FLUCONAZOLE 150MG SECNIDAZOLE 1G

Dose

For adults: Azithromycin 1 g orally single dose, Fluconazole 150 mg orally single dose, Secnidazole 1 g orally single dose, all taken together. Not recommended for pediatric use or during pregnancy and lactation unless specifically indicated by a specialist. Dose adjustments may be required in severe hepatic or renal impairment.

Mechanism of action

Indications

Uncomplicated vulvovaginal candidiasis, trichomoniasis, bacterial vaginosis, mixed vaginal infections, syndromic management of vaginal discharge.

Side effects

Pregnancy category

Category C

Precautions

Contraindications

Hypersensitivity to azithromycin, fluconazole, secnidazole, macrolides, azoles, or nitroimidazoles, severe hepatic impairment, QT prolongation, concurrent use of drugs metabolized by CYP3A4 (for fluconazole), pregnancy (for secnidazole).