Clinical Pharmacy womens health

epilepsy in pregnancy

Topic overview

Start with the big picture

The lesson follows care across preconception, pregnancy, delivery, and postpartum. It emphasizes aiming for seizure freedom with monotherapy at the lowest effective dose before conception, reviewing medicine-related fetal risks, and providing folic acid supplementation. It also introduces how pregnancy may alter lamotrigine and levetiracetam clearance and why levels and doses may need follow-up. Other areas include prompt management of acute seizures, additional considerations with enzyme-inducing medicines, fetal anomaly screening, breastfeeding, and postpartum dose reduction. Counseling addresses adherence, teratogenicity, and avoiding abrupt medication changes. Together, these topics frame decisions around balancing seizure control with safety for both parent and baby.

Learning objectives

What you'll learn

  • Describe preconception goals for seizure control and medicine planning.
  • Identify key considerations when selecting antiseizure medicines during pregnancy.
  • Explain why medicine levels and doses may need review during and after pregnancy.
  • Outline acute seizure, fetal screening, and breastfeeding considerations.
  • Recognize counseling and safety issues across pregnancy and postpartum.
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