Clinical Pharmacy respiratory system

emphysema

Topic overview

Start with the big picture

Emphysema is associated with cigarette smoking, biomass exposure, and inherited α1-antitrypsin deficiency. Typical features include progressive exertional dyspnea, little productive cough, hyperinflation, quiet breath sounds, and hyperresonance; imaging may show a flattened diaphragm or bullae. Diagnosis is supported by post-bronchodilator spirometry showing an FEV1/FVC ratio below 0.70. Care combines smoking cessation and preventive measures with symptom-guided inhaled medicines, pulmonary rehabilitation, and attention to nutrition and respiratory irritants. Selected patients may benefit from long-term oxygen or α1-antitrypsin infusions. Follow-up includes checking inhaler technique and adherence, lung function, weight, and exacerbations. The full lesson develops these principles and their clinical criteria in greater detail.

Learning objectives

What you'll learn

  • Identify major environmental and genetic causes of emphysema.
  • Recognize common clinical and examination findings associated with emphysema.
  • Describe the spirometric criterion used to support COPD diagnosis.
  • Summarize broad pharmacologic, preventive, and non-pharmacologic management approaches.
  • List key areas to assess during follow-up.
Ready for the complete lesson?

Continue your study

Work through the complete notes and reinforce the topic with the study tools available in the full lesson.

PharmaProLearn

Excel Beyond Limits