Clinical Pharmacy respiratory system

tuberculosis and HIV

Topic overview

Start with the big picture

The lesson covers TB screening in people living with HIV, including symptom review and IGRA or TST, with chest imaging when test results are positive. It introduces isoniazid preventive therapy with pyridoxine for latent TB and outlines the standard approach to active TB treatment. Key considerations include interactions between rifamycins and antiretroviral drugs, selecting and timing ART, and recognizing and managing IRIS. The topic also addresses monitoring for treatment toxicity, special population considerations, prophylaxis, adherence, and drug-resistant TB. Together, these areas show why TB/HIV care involves more than choosing a regimen: treatment plans must account for safety, interactions, and follow-up.

Learning objectives

What you'll learn

  • Describe TB screening steps for people living with HIV.
  • Distinguish preventive therapy for latent TB from treatment of active TB.
  • Identify key interactions between rifamycins and antiretroviral medicines.
  • Explain considerations for ART timing and IRIS management.
  • Recognize monitoring, prophylaxis, and adherence priorities in TB/HIV care.
Ready for the complete lesson?

Continue your study

Work through the complete notes and reinforce the topic with the study tools available in the full lesson.

PharmaProLearn

Excel Beyond Limits