Clinical Pharmacy cardiovascular system

coronary heart disease

Topic overview

Start with the big picture

The lesson connects coronary plaque formation with stable angina and acute coronary syndromes, including unstable angina, NSTEMI, and STEMI. It reviews modifiable risks such as dyslipidemia, hypertension, diabetes, smoking, obesity, and physical inactivity, alongside age and family history. Diagnosis is approached through the pattern of chest discomfort, troponin results, and 12-lead ECG changes. Management topics include initial ACS therapy, STEMI reperfusion choices, antiplatelet and anticoagulant treatment, and long-term secondary prevention. Symptom control and medication-related contraindications are also part of the broader topic, helping learners relate clinical findings to pharmacy care.

Learning objectives

What you'll learn

  • Describe the role of coronary atherothrombotic plaque in stable angina and acute coronary syndromes.
  • Distinguish modifiable from non-modifiable coronary heart disease risk factors.
  • Relate angina symptoms, troponin findings, and ECG patterns to clinical assessment.
  • Outline the major components of ACS treatment and STEMI reperfusion.
  • Identify key themes in long-term secondary prevention and symptom control.
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