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Infection follows fecal–oral ingestion of cysts, often through contaminated food or water; pig contact and poor sanitation are important risk factors. The organism’s trophozoites can invade the colonic mucosa, producing illness that ranges from asymptomatic carriage to watery or bloody diarrhea and abdominal pain. Diagnosis relies on identifying characteristic forms in stool or colonic biopsy. Treatment selection involves weighing the listed antiparasitic options and their adverse-effect considerations. For severe disease, supportive care is important, while antimotility agents should be avoided. Prevention focuses on hygiene, safe water, and sanitation. The full lesson also addresses follow-up for persistent infection and public-health considerations.