Clinical Pharmacy CNS disorders

cerebrovascular accidents

Topic overview

Start with the big picture

The lesson follows stroke care from initial classification through acute management and prevention. For ischemic stroke, it covers eligibility and contraindications for IV alteplase, the role of mechanical thrombectomy in selected large-vessel occlusions, and blood-pressure management when thrombolysis is or is not used. It also introduces antiplatelet treatment, anticoagulation for cardioembolic stroke, statin therapy, and control of modifiable risk factors. The hemorrhagic-stroke section focuses on reversing anticoagulants, managing blood pressure in intracerebral hemorrhage, and using nimodipine in subarachnoid hemorrhage. Together, these topics show why treatment choices depend on stroke type, timing, imaging, bleeding risk, and the patient’s clinical context.

Learning objectives

What you'll learn

  • Distinguish ischemic from hemorrhagic stroke using the initial imaging approach described.
  • Summarize key alteplase eligibility considerations and safety checks.
  • Describe treatment pathways for antiplatelet and cardioembolic stroke prevention.
  • Identify major pharmacologic approaches to hemorrhagic stroke management.
  • Recognize risk-factor control strategies used to reduce recurrent stroke risk.
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