Medical Physiology Special Topics

Exercise Physiology

Topic overview

Start with the big picture

During exercise, heart rate and stroke volume rise, increasing cardiac output, while blood flow shifts toward active skeletal muscle. Oxygen consumption and ventilation increase; VO₂ max reflects aerobic fitness, and the ventilatory threshold marks a change in the breathing response. Multiple energy systems contribute, with fuel use varying by exercise intensity. After activity, excess post-exercise oxygen consumption supports recovery processes. The lesson also distinguishes slow and fast muscle fibers and compares adaptations to aerobic and resistance training. Further topics include acute hormonal responses, temperature regulation and fluid balance, exercise at altitude, and additional considerations such as cardiac morphology, overtraining, aging, and female physiology.

Learning objectives

What you'll learn

  • Describe immediate cardiovascular changes and blood-flow redistribution during exercise.
  • Explain VO₂ max, ventilatory threshold, and how exercise intensity influences fuel selection.
  • Distinguish the energy systems and muscle fiber types involved in exercise.
  • Compare chronic adaptations to aerobic and resistance training.
  • Identify hormonal, thermoregulatory, and altitude-related responses to exercise.
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