Medical Physiology Nervous System Physiology

Higher Functions

Topic overview

Start with the big picture

The lesson surveys higher functions beyond basic sensory and motor activity. It covers cortical contributions to judgment, decision-making, social behavior, and language, including the distinct roles of Broca’s and Wernicke’s areas. It introduces sleep and wakefulness through the roles of the hypothalamus, brainstem circuits, and reticular activating system, alongside the alternating NREM and REM stages of sleep. Memory is explored through short-term and long-term forms, the distinction between declarative facts and non-declarative skills, and the role of hippocampal long-term potentiation in learning and memory formation. The limbic system’s contributions to emotion, motivation, and memory are also highlighted, with attention to the amygdala and hippocampus.

Learning objectives

What you'll learn

  • Relate the prefrontal cortex to judgment, decision-making, and social behavior.
  • Distinguish Broca’s and Wernicke’s areas by their language functions and lesion effects.
  • Describe key structures involved in regulating sleep and wakefulness.
  • Differentiate short-term memory from declarative and non-declarative long-term memory.
  • Explain the limbic system’s roles in emotion, motivation, and memory.
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