Compounding Techniques for Different Dosage Forms
Start with the big picture
The topic surveys practical methods used across common dosage forms. Powder techniques include trituration, geometric dilution, pulverization by intervention, levigation, spatulation, and sifting, each suited to a different mixing or particle-handling need. Wet granulation and direct compression are presented as distinct approaches to tablet preparation. For semisolids, the lesson contrasts fusion with cold incorporation. Emulsion preparation covers dry gum, wet gum, and the bottle method, while suspension compounding emphasizes wetting and gradual vehicle addition. The final section introduces sterile filtration and aseptic transfer for ophthalmic and parenteral solutions. Together, these methods provide a framework for choosing a compounding approach based on ingredients and dosage form.
What you'll learn
- Describe the purposes of common powder manipulation and blending techniques.
- Distinguish wet granulation from direct compression in tablet preparation.
- Compare fusion and cold incorporation for semisolid preparation.
- Identify the dry gum, wet gum, and bottle methods for emulsions.
- Summarize key steps in suspension and sterile solution compounding.
Continue your study
Work through the complete notes and reinforce the topic with the study tools available in the full lesson.
