Micromeritics and Powder Properties
Start with the big picture
Powder performance depends on several linked micromeritic properties. Particle size and its distribution can influence dose uniformity and dissolution, while specific surface area is related to particle size and can affect dissolution and adsorption. Shape influences flow, packing, and compaction. Density measurements, compressibility and flow indices, angle of repose, and porosity provide ways to characterize powder handling and structure. The topic also connects these measurements to practical decisions: granulation can improve flow and density, and polymorphism can alter density and surface area. Together, these concepts help frame the role of powder characterization in preformulation and pharmaceutical processing.
What you'll learn
- Explain how particle size and distribution relate to powder performance.
- Identify methods used to assess particle size and specific surface area.
- Distinguish true, bulk, and tapped density measurements.
- Interpret common indices of powder flow and compressibility.
- Describe how porosity, granulation, and polymorphism affect processing.
Continue your study
Work through the complete notes and reinforce the topic with the study tools available in the full lesson.
