Pharmacognosy Recent Advances in Pharmacognosy

Personalized herbal medicine

Topic overview

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Precision phytotherapy draws on complementary technologies to characterize both the patient and the herbal product. Pharmacogenomics examines how genetic variation in drug-metabolizing enzymes and transporters may affect herb response and herb–drug interactions. Chemotyping and botanical authentication help ensure that selected materials have appropriate composition and identity, while metabolomics and microbiome analysis can illuminate changes in metabolism and constituent bioavailability. The approach also encompasses epigenetic and dietary data, computational analysis, and monitoring through biosensors or wearables. Formulation technologies, including targeted delivery systems and customized dosage forms, offer further ways to address variability. Together, these methods aim to align herbal interventions with individual needs, supported by attention to clinical evidence, regulation, and risk management.

Learning objectives

What you'll learn

  • Explain how genetic variation can inform herbal selection and interaction assessment.
  • Describe the roles of chemotyping, DNA barcoding, and NGS in product selection and authentication.
  • Identify how metabolomic and microbiome data may support monitoring and personalization.
  • Outline how digital tools and formulation technologies contribute to precision phytotherapy.
  • Recognize the importance of clinical evidence, regulation, and safety management.
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