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Pharmacology Antianginal Drugs

Introduction to Angina

Topic overview

Start with the big picture

Angina may occur when reduced blood flow limits oxygen delivery to the myocardium; atherosclerotic plaque in the coronary arteries is a leading cause. The topic distinguishes stable angina, often triggered by exertion or stress and relieved by rest or nitroglycerin, from unstable angina, which may occur at rest and is a medical emergency. It also introduces variant angina, associated with coronary artery spasms, and microvascular angina, related to dysfunction of small coronary arteries. The lesson’s broader structure covers risk factors, causes, signs and symptoms, diagnosis, and management. Management may involve medications, lifestyle changes, and, when necessary, procedures such as angioplasty or coronary artery bypass grafting.

Learning objectives

What you'll learn

  • Define angina and relate it to myocardial ischemia.
  • Distinguish stable, unstable, variant, and microvascular angina.
  • Identify atherosclerosis as a leading cause of reduced myocardial blood flow.
  • Outline the lesson’s approach to symptoms, diagnosis, and management.
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