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Pharmacology Toxicology

Environmental and Occupational Toxicology

Topic overview

Start with the big picture

Exposure route helps shape risk: inhaled gases, vapors, and particles can be absorbed through the alveoli, while skin contact and ingestion can also produce local or systemic effects. OSHA PEL, ACGIH TLV, and NIOSH REL are airborne exposure-limit frameworks; Biological Exposure Indices provide a way to monitor internal dose. The lesson then turns to particulate matter and selected toxicants, including carbon monoxide, cyanide, heavy metals, industrial chemicals, and dusts. For each, the source snapshot highlights relevant settings, mechanisms or target organs, and prevention or management considerations. Together, these topics provide a framework for recognizing environmental and occupational hazards and understanding why exposure assessment matters.

Learning objectives

What you'll learn

  • Describe inhalation, dermal, and ingestion routes of environmental and workplace exposure.
  • Distinguish airborne exposure limits from biological monitoring of internal dose.
  • Summarize health effects associated with particulate matter and selected toxicants.
  • Identify exposure settings and management considerations for major workplace toxicants.
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